Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 7/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199832 | 1.00 | PRCP (0.56) | PRCPHTR2CSLC18A3ITGA4ITGB7 | |
| SCHEMBL8200402 | 0.84 | HTR2C (0.48) | PRCPHTR2CSLC18A3CCR5 | |
| SCHEMBL8199643 | 0.83 | CCR5 (0.48) | PRCPHTR2CSLC18A3CCR5 | |
| SCHEMBL8198484 | 0.83 | HTR2C (0.42) | HTR2CSLC18A3 | |
| SCHEMBL8203423 | 0.81 | DRD3 (0.43) | PRCPHTR2CSLC18A3ADRA1DADRA1A | |
| SCHEMBL8203121 | 0.81 | DRD3 (0.43) | HTR2CSLC18A3ADRA1DADRA1AADRA1B | |
| SCHEMBL8200414 | 0.81 | PRCP (0.44) | PRCPHTR2CSLC18A3CCR5ALDH1A1 | |
| SCHEMBL8589678 | 0.81 | SIGMAR1 (0.44) | HTR2CKDM4E | |
| SCHEMBL8588349 | 0.81 | SIGMAR1 (0.44) | HTR2CKDM4E | |
| SCHEMBL8200419 | 0.81 | SIGMAR1 (0.44) | HTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | claimed |
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |