SCHEMBL8193399

SCHEMBL8193399

CCOc1nc(C(F)(F)F)cc(=O)n1-c1cc(F)c(C#N)cc1F

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALPL P05186 7/20 0.39
BCAT2 O15382 9/20 0.39
BCAT1 P54687 8/20 0.39
ALPI P09923 7/20 0.38
ALDH1A1 P00352 1/20 0.35
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7082848 0.79 BCAT2 (0.38) ALPLBCAT2BCAT1ALPIALDH1A1
SCHEMBL7694103 0.79 MEN1 (0.40) ALPLBCAT2BCAT1ALPIALDH1A1
SCHEMBL10533654 0.78 ALDH1A1 (0.38) ALPLALPIALDH1A1
SCHEMBL10531875 0.78 ALPL (0.37) ALPLALPIALDH1A1
SCHEMBL10532184 0.78 ALPL (0.39) ALPLALPIALDH1A1
SCHEMBL10529969 0.77 ALPL (0.40) ALPLALPIALDH1A1
SCHEMBL10530817 0.77 BCAT2 (0.41) ALPLBCAT2BCAT1ALPIALDH1A1
SCHEMBL10530882 0.76 PGK1 (0.38) ALPLBCAT2BCAT1ALPIALDH1A1
SCHEMBL10531878 0.75 ALPL (0.37) ALPLALPIALDH1A1
SCHEMBL10530877 0.75 PPOX (0.40) ALPLALPIALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6110870-A SELECTIVE HERBICIDE FOR KILLING WEEDS BUT NOT OF A WHEAT, CORN OR SOYBEAN CROP, COMPOUNDS SUCH AS 1-(4-CYANO-2,5-DIFLUORO-PHENYL)-3,6-DIHYDRO-2,6-DIOXO-3-ETHYL-4 -TRIFLUOROMETHYL-1(2H)-PYRIMIDINE BAYER AKTIENGESELLSCHAFT (DE) 2000-08-29 US disclosed
EP-0648749-B1 N-cyanoaryl nitrogencontaining heterocycles BAYER AG (DE) 1997-12-10 EP disclosed
US-5681794-A HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1997-10-28 US disclosed
US-5593945-A HERBICIDES AND CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
EP-0648749-A2 N-cynanoaryl nitrogencontaining heterocycles BAYER AG (DE) 1995-04-19 EP disclosed