Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194924 | 0.90 | — | — | |
| SCHEMBL13221 | 0.86 | RAB9A (0.32) | PCSK9 | |
| SCHEMBL8121 | 0.86 | RAB9A (0.32) | PCSK9 | |
| SCHEMBL14135 | 0.86 | RAB9A (0.32) | PCSK9 | |
| SCHEMBL8199752 | 0.86 | ADRB2 (0.33) | PCSK9 | |
| SCHEMBL8196578 | 0.86 | NOS1 (0.34) | — | |
| SCHEMBL8199304 | 0.85 | NOS1 (0.34) | — | |
| SCHEMBL25504021 | 0.83 | ELANE (0.32) | — | |
| SCHEMBL6764378 | 0.82 | SYK (0.41) | — | |
| SCHEMBL17560519 | 0.81 | ELANE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078723-A1 | PROCESS FOR THE PREPARATION OF BUTOXYCARBONYLIMINO COMPOUNDS AND INTERMEDIATES THEREFOR | GLAXO GROUP LIMITED (GB) | 2000-12-28 | — | — | WO | disclosed |