Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202886 | 0.81 | ALDH1A1 (0.34) | HTR7HTR1A | |
| SCHEMBL8202899 | 0.80 | HTR1A (0.39) | HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL7643056 | 0.78 | HTR2C (0.33) | HTR2B | |
| SCHEMBL4079021 | 0.77 | PDCD1 (0.33) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| SCHEMBL5694274 | 0.76 | PDCD1 (0.37) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| SCHEMBL5709148 | 0.75 | PDCD1 (0.34) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| SCHEMBL6909072 | 0.75 | — | — | |
| SCHEMBL7525652 | 0.74 | PDCD1 (0.36) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| SCHEMBL4603520 | 0.74 | PDCD1 (0.36) | CHRNB2CHRNA4BRD4PDCD1CD274 | |
| SCHEMBL28550963 | 0.74 | PDCD1 (0.36) | CHRNB2CHRNA4BRD4PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | claimed |
| US-6136993-A | CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT | THE DOW CHEMICAL COMPANY (US) | 2000-10-24 | — | — | US | disclosed |
| US-6084115-A | METAL DIENE-CONTAINING COMPLEXES BY REACTION WITH THE DIVALENT DERIVATIVE OF A BRIDGED BIDENTATE LIGAND; METALLOCENES; RACEMIC ISOMER USED TO PREPARE ISOTACTIC POLYOLEFINS, E.G., CRYSTALLINE POLYPROPYLENE. | THE DOW CHEMICAL COMPANY (US) | 2000-07-04 | — | — | US | disclosed |