Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893624 | 0.86 | CNR1 (0.33) | CNR1GPR55CNR2CTSK | |
| SCHEMBL8200737 | 0.83 | L3MBTL1 (0.36) | CNR1GPR55CNR2 | |
| SCHEMBL6201097 | 0.80 | CNR1 (0.38) | CNR1MTNR1AMTNR1BGPR55CNR2 | |
| SCHEMBL8202222 | 0.78 | CNR1 (0.38) | CNR1MTNR1AMTNR1BGPR55CNR2 | |
| SCHEMBL6202055 | 0.74 | CNR1 (0.38) | CNR1MTNR1AMTNR1BGPR55CNR2 | |
| SCHEMBL29799247 | 0.69 | MTNR1A (0.52) | MTNR1AMTNR1BGPR55ALDH1A1LTA4H | |
| SCHEMBL7015694 | 0.69 | MTNR1A (0.52) | MTNR1AMTNR1BGPR55ALDH1A1LTA4H | |
| SCHEMBL9231286 | 0.69 | MTNR1A (0.49) | MTNR1AMTNR1BGPR55ALDH1A1LTA4H | |
| SCHEMBL8892569 | 0.68 | L3MBTL1 (0.33) | CNR1GPR55CNR2CTSK | |
| SCHEMBL6200633 | 0.68 | MMP2 (0.38) | CNR1CNR2ALDH1A1CTSKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971744-A2 | COMBINATION THERAPY EMPLOYING ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998040375-A2 | COMBINATION OF ILEAL BILE ACID TRANSPORT INHIBITING BENZOTHIEPINES AND HMG Co-A REDUCTASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-09-17 | — | — | WO | disclosed |