Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571899 | 0.84 | ALDH1A1 (0.37) | CNR1HTTLMNACYP1A2CYP2C9 | |
| SCHEMBL7826432 | 0.80 | POLB (0.36) | CYP1A2CYP2C9CYP2C19CNR2TSHR | |
| SCHEMBL8893624 | 0.76 | CNR1 (0.33) | L3MBTL1CNR1HTTLMNAMMP2 | |
| SCHEMBL6201251 | 0.74 | LMNA (0.35) | CNR1HTTLMNACYP1A2CYP2C9 | |
| SCHEMBL8892564 | 0.73 | LMNA (0.34) | CNR1HTTLMNACNR2GPR18 | |
| SCHEMBL8202225 | 0.68 | CNR1 (0.37) | CNR1CNR2CTSKGPR55 | |
| SCHEMBL8201728 | 0.67 | P2RX4 (0.34) | L3MBTL1HTTLMNACYP2C9CNR2 | |
| SCHEMBL6201198 | 0.66 | AR (0.36) | L3MBTL1CNR1HTTLMNACNR2 | |
| SCHEMBL8893617 | 0.63 | CNR1 (0.34) | L3MBTL1CNR1HTTLMNACNR2 | |
| SCHEMBL7026728 | 0.62 | CSNK1E (0.47) | MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033882-A1 | NOVEL BENZOTHIEPINES HAVING ACTIVITY AS INHIBITORS OF ILEAL BILE ACID TRANSPORT AND TAUROCHOLATE UPTAKE | G.D. SEARLE AND CO. (US) | 1997-09-18 | — | — | WO | disclosed |