SCHEMBL376004

SCHEMBL376004

CCCCCCCCCCCCCCO[Si](C)(C)CCCS

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
CA1 P00915 8/20 0.31
CA2 P00918 8/20 0.31
CA9 Q16790 7/20 0.31
LPAR3 Q9UBY5 6/20 0.31
LPAR2 Q9HBW0 5/20 0.31
CA12 O43570 3/20 0.31
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
LPAR1 Q92633 2/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375472 1.00 THRB (0.32) THRBALDH1A1TDP1MEN1HTT
SCHEMBL28419655 0.94 ALDH1A1 (0.32) THRBALDH1A1TDP1MEN1HTT
SCHEMBL6567765 0.94 ALDH1A1 (0.32) THRBALDH1A1TDP1MEN1HTT
SCHEMBL375539 0.92 ADRB2 (0.32)
SCHEMBL820390 0.89 HTT (0.44) THRBALDH1A1TDP1MEN1HTT
SCHEMBL375947 0.85
SCHEMBL8161878 0.85 CA1 (0.33) THRBALDH1A1TDP1MEN1HTT
SCHEMBL15984917 0.85 CA1 (0.33) THRBALDH1A1TDP1MEN1HTT
SCHEMBL4539608 0.84 THRB (0.32) THRBALDH1A1TDP1MEN1HTT
SCHEMBL375555 0.84 THRB (0.32) THRBALDH1A1TDP1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US claimed
US-20060252952-A1 Process for preparing mercaptoorganyl (alkoxysilanes) DEGUSSA AG (DE) 2006-11-09 US claimed
US-12139635-B2 Coatings for waterproofing electronic components HENKEL AG & CO. KGAA (DE) 2024-11-12 US disclosed
US-20220002559-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2022-01-06 US disclosed
WO-2020197963-A1 COATINGS FOR WATERPROOFING ELECTRONIC COMPONENTS HENKEL AG & CO. KGAA (DE) 2020-10-01 WO disclosed
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2014-01-02 US disclosed
EP-2408785-A1 PROCESS FOR PREPARING ORGANOSILANES Evonik Degussa GmbH (DE) 2012-01-25 EP disclosed
WO-2010105434-A1 PROCESS FOR PREPARING ORGANOSILANES EVONIK DEGUSSA GMBH (DE) 2010-09-23 WO disclosed
US-7518009-B2 Process for preparing mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2009-04-14 US disclosed
US-7501534-B2 Process for the preparation of organosilanes DEGUSSA AG (DE) 2009-03-10 US disclosed
US-7339067-B2 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2008-03-04 US disclosed
EP-1637535-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa GmbH (DE) 2006-03-22 EP disclosed
EP-1634884-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa GmbH (DE) 2006-03-15 EP disclosed
US-20060052621-A1 Process for producing mercaptoorganyl (alkoxysilane) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-20060052622-A1 Process for the preparation of mercaptoorganyl (alkoxysilanes) EVONIK DEGUSSA GMBH (DE) 2006-03-09 US disclosed
US-6995280-B2 Process for preparing (mercaptoorganyl)alkoxysilanes DEGUSSA AG (DE) 2006-02-07 US disclosed
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes EVONIK OPERATIONS GMBH (DE) 2005-06-09 US disclosed
EP-1538152-A1 Process for the preparation of (mercaptoorganyl)-alkoxysilanen Degussa AG (DE) 2005-06-08 EP disclosed
EP-1529782-A1 Process for preparing mercaptoorganyl alkoxy silanes Degussa AG (DE) 2005-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124821-A1 Process for preparing (mercaptoorganyl)alkoxysilanes ADH1C, ADH1A, MPST THRB 4696/4885ALDH1A1 670/4885TDP1 4712/4885
US-20050124822-A1 Process for the preparation of (mercaptoorganyl)alkoxysilanes MPST, ADH1A, ADH1C THRB 4640/4885ALDH1A1 208/4885TDP1 4748/4885
US-20140005432-A1 PROCESS FOR PREPARING ORGANOSILANES MPST, STS, CYP2S1 THRB 3983/4885ALDH1A1 1390/4885TDP1 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.