Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204774 | 0.81 | HPGD (0.67) | ESR1ESR2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10785217 | 0.80 | ESR1 (0.64) | ESR1ESR2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10782877 | 0.79 | ALDH1A1 (0.59) | HPGDHSD17B10ALDH1A1KDM4EKMT2A | |
| SCHEMBL10499780 | 0.77 | ACHE (0.44) | ESR1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4182982 | 0.75 | HTT (0.49) | HPGDALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL3834888 | 0.75 | KCNMA1 (0.58) | ESR1ESR2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL3405509 | 0.75 | ALDH1A1 (0.46) | HPGDALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL8209348 | 0.75 | HPGD (0.58) | ESR1ESR2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL11876495 | 0.74 | TLR8 (0.41) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL10686808 | 0.74 | HSD17B10 (0.71) | ESR1ESR2HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149442-A1 | Atypical antipsychotic agents having low affinity for the D2 receptor | KAPUR SHITIJ | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149442-A1 | Atypical antipsychotic agents having low affinity for the D2 receptor | DRD2, OPRD1, GRIN2A | ESR1 873/4885ESR2 459/4885HPGD 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.