Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 6/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709456 | 0.90 | MEN1 (0.50) | PER2FABP4FABP5GRIN1GRIN2A | |
| SCHEMBL7310378 | 0.80 | PARP1 (0.46) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL5658778 | 0.78 | CA12 (0.45) | ALDH1A1MEN1TP53CYP1A2CYP3A4 | |
| SCHEMBL29941758 | 0.78 | ALDH1A1 (0.64) | FABP4FABP5GRIN1GRIN2AGRIN2B | |
| SCHEMBL10090172 | 0.78 | ALDH1A1 (0.64) | FABP4FABP5GRIN1GRIN2AGRIN2B | |
| SCHEMBL11195247 | 0.77 | POLB (0.65) | ALDH1A1MEN1CYP1A2TSHRMAPK1 | |
| SCHEMBL5637077 | 0.75 | HTR2A (0.54) | MEN1TP53HTR2AKMT2AHDAC1 | |
| SCHEMBL4552481 | 0.74 | FABP4 (0.68) | FABP4FABP5GRIN1GRIN2AGRIN2B | |
| SCHEMBL4552166 | 0.74 | FABP4 (0.64) | FABP4FABP5GRIN1GRIN2AGRIN2B | |
| SCHEMBL8209253 | 0.74 | FABP4 (0.51) | FABP4FABP5GRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130236416-A1 | SURFACE MODIFIED COLLOIDAL PARTICLES | CLEMSON UNIVERSITY (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130236416-A1 | SURFACE MODIFIED COLLOIDAL PARTICLES | CLEMSON UNIVERSITY (US) | 2013-09-12 | — | — | US | disclosed |
| US-20100292249-A1 | MANUFACTURE OF RIMCAZOLE | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-11-18 | — | — | US | disclosed |
| US-20100292249-A1 | MANUFACTURE OF RIMCAZOLE | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-11-18 | — | — | US | disclosed |
| WO-2008040950-A1 | MANUFACTURE OF RIMCAZOLE | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2008-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292249-A1 | MANUFACTURE OF RIMCAZOLE | P2RX5, CYP3A5, ADRA2C | PER2 3573/4885FABP4 3133/4885FABP5 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.