Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907118 | 0.73 | HSD11B1 (0.38) | SLC6A3KMT2ADHFRPDE4BCYP1A2 | |
| SCHEMBL23907104 | 0.72 | DHFR (0.37) | SLC6A3KMT2ADHFRPDE4B | |
| SCHEMBL14422348 | 0.71 | ALDH1A1 (0.51) | SLC6A3HPGDKMT2A | |
| SCHEMBL8209894 | 0.71 | DHFR (0.38) | HPGDKMT2ADHFRSMN1; SMN2L3MBTL1 | |
| SCHEMBL5618972 | 0.71 | MEN1 (0.43) | HPGDKMT2ADHFRPDE4BSMN1; SMN2 | |
| SCHEMBL563008 | 0.70 | HSD11B1 (0.38) | SLC6A3HPGDKMT2ADHFRPDE4B | |
| SCHEMBL18868394 | 0.70 | ALDH1A1 (0.47) | SLC6A3HPGDKMT2APDE4B | |
| SCHEMBL10203685 | 0.70 | KDM4E (0.39) | SLC6A3HPGDKDM4EPDE4BSMN1; SMN2 | |
| SCHEMBL3905489 | 0.69 | CA12 (0.46) | SLC6A3HPGDKMT2AKDM4ECFTR | |
| SCHEMBL23907117 | 0.69 | HSD11B1 (0.35) | SLC6A3KMT2ADHFRPDE4BCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |