Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199930 | 0.89 | MGLL (0.52) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8206605 | 0.89 | NPC1 (0.48) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8210425 | 0.89 | EPHX2 (0.51) | KMT2ASMN1; SMN2CA1CA2ALDH1A1 | |
| SCHEMBL8210714 | 0.88 | KDM4E (0.51) | MEN1KMT2ASMN1; SMN2KDM4ESCD | |
| SCHEMBL8212457 | 0.86 | AKR1B1 (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8212903 | 0.86 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2KDM4ESCD | |
| SCHEMBL8206984 | 0.86 | ALDH1A1 (0.54) | MEN1KMT2ASMN1; SMN2KDM4ESCD | |
| SCHEMBL8199066 | 0.85 | LMNA (0.52) | MEN1KMT2ASMN1; SMN2HPGDMAPT | |
| SCHEMBL8245383 | 0.85 | ROCK2 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8212431 | 0.82 | TDP1 (0.54) | MEN1KMT2ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |