Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15726601 | 1.00 | HRH3 (0.58) | HRH3HSP90AA1ALDH1A1FAAHMEN1 | |
| SCHEMBL15417860 | 0.98 | HRH3 (0.56) | HRH3HSP90AA1ALDH1A1FAAHMEN1 | |
| SCHEMBL14845707 | 0.92 | ALDH1A1 (0.52) | HRH3HSP90AA1ALDH1A1FAAHMEN1 | |
| SCHEMBL15726667 | 0.86 | DGKA (0.56) | HRH3FAAHMEN1KMT2A | |
| SCHEMBL23392423 | 0.85 | ALDH1A1 (0.63) | HRH3HSP90AA1ALDH1A1FAAHMEN1 | |
| SCHEMBL10689611 | 0.85 | ALDH1A1 (0.63) | HRH3HSP90AA1ALDH1A1FAAHMEN1 | |
| SCHEMBL11922964 | 0.85 | ALDH1A1 (0.63) | HRH3HSP90AA1ALDH1A1FAAHMEN1 | |
| SCHEMBL12328518 | 0.85 | TSHR (0.46) | HRH3ALDH1A1MEN1KMT2APPARG | |
| SCHEMBL10179 | 0.84 | HDAC3 (0.46) | HRH3ALDH1A1MEN1KMT2ACES2 | |
| SCHEMBL7620414 | 0.83 | SELP (0.49) | HRH3HSP90AA1ALDH1A1FAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10478492-B2 | Modifications of therapeutic agents for enhanced delivery to target sites | CLARIA PARTIKULA LLC (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180028647-A1 | MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES | CLARIA ODIN LLC | 2018-02-01 | — | — | US | disclosed |
| US-20180028647-A1 | MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES | CLARIA ODIN LLC | 2018-02-01 | — | — | US | disclosed |
| EP-0968998-A1 | Cosmetic compositions, ceramide analogues with anti-elastase activity and process for their preparation | ELF ATOCHEM S.A. (FR) | 2000-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028647-A1 | MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES | PDK1, PC, PDK2 | HRH3 3172/4885HSP90AA1 605/4885ALDH1A1 1505/4885 |
| US-10478492-B2 | Modifications of therapeutic agents for enhanced delivery to target sites | PDK1, PC, PDK2 | HRH3 3172/4885HSP90AA1 605/4885ALDH1A1 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.