Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889393 | 0.92 | KMT2A (0.52) | MGAMAMY1AGLO1TP53KMT2A | |
| SCHEMBL8206343 | 0.85 | MAPT (0.47) | TP53ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8208116 | 0.83 | MAPT (0.50) | TP53KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL8200088 | 0.82 | FLT3 (0.44) | MGAMAMY1ATP53KMT2ARAB9A | |
| SCHEMBL8206432 | 0.81 | TAAR1 (0.54) | TP53KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL8212434 | 0.80 | SMN1; SMN2 (0.39) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL8200396 | 0.80 | ALDH1A1 (0.44) | KMT2ARAB9AALDH1A1MEN1MAPT | |
| SCHEMBL8198895 | 0.79 | SMN1; SMN2 (0.38) | KMT2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL8200375 | 0.78 | ALDH1A1 (0.41) | KMT2ARAB9AALDH1A1MEN1MAPT | |
| SCHEMBL8211459 | 0.78 | MGAM (0.77) | MGAMAMY1AGLO1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |