Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889393 | 0.84 | KMT2A (0.52) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8200088 | 0.81 | FLT3 (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8207643 | 0.81 | MGAM (0.51) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8206343 | 0.80 | MAPT (0.47) | MAPTALDH1A1HPGDGAAALOX15 | |
| SCHEMBL8208116 | 0.77 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL8209525 | 0.76 | KMT2A (0.37) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8211806 | 0.76 | PYGL (0.36) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8207229 | 0.75 | ALOX15 (0.40) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL8199872 | 0.74 | TAAR1 (0.44) | TAAR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8212891 | 0.74 | ALDH1A1 (0.40) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |