SCHEMBL8207778

SCHEMBL8207778

CC(=O)NC(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
CRHBP P24387 2/20 0.56
CRHR2 Q13324 2/20 0.56
RXFP1 Q9HBX9 1/20 0.56
LMNA P02545 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CNR2 P34972 2/20 0.54
EGFR P00533 2/20 0.53
ERBB2 P04626 2/20 0.53
POLB P06746 2/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8195021 0.81 ACLY (0.44) ALDH1A1MEN1KMT2ACRHBPCRHR2
SCHEMBL15948799 0.81 GAA (0.59) ALDH1A1MEN1KMT2ALMNARAB9A
SCHEMBL8205134 0.80 L3MBTL1 (0.50) ALDH1A1MEN1KMT2ALMNAL3MBTL1
SCHEMBL8013439 0.80 MEN1 (0.61) ALDH1A1MEN1KMT2ACRHBPCRHR2
SCHEMBL6244680 0.80 POLB (0.67) ALDH1A1MEN1KMT2ALMNANPC1
SCHEMBL10462228 0.79 NLRP3 (0.51) ALDH1A1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL10926979 0.79 POLB (0.53) ALDH1A1MEN1KMT2ACRHBPCRHR2
SCHEMBL29141288 0.79 EGFR (0.47) KMT2AEGFRERBB2
SCHEMBL7905681 0.78 HTT (0.71) ALDH1A1MEN1KMT2ALMNANPC1
SCHEMBL4161901 0.78 LMNA (0.53) ALDH1A1MEN1KMT2ACRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1315780-C Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2007-05-16 CN disclosed
CN-1243720-C Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2006-03-01 CN disclosed
CN-1243719-C Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2006-03-01 CN disclosed
CN-1680273-A Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 2005-10-12 CN disclosed
CN-1526696-A Process for producing N- [ 1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide 住友化学工业株式会社 2004-09-08 CN disclosed
CN-1524845-A Process for producing n-(1-(2,4-dichlorophenyl)ethyl)-2- cyano-3,3-dimethylbutanamide 住友化学工业株式会社 2004-09-01 CN disclosed
CN-1153762-C Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide 住友化学工业株式会社 2004-06-16 CN disclosed
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed
EP-0735018-B1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL CO (JP) 1999-07-21 EP disclosed
US-5739401-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-14 US disclosed
EP-0735018-A1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed
CN-1131146-A Process for producing N- [1- (2, 4-dichlorophenyl) ethyl ] -2-cyano-3, 3-dimethylbutanamide SUMITOMO CHEMICAL CO (JP) 1996-09-18 CN disclosed