Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279899 | 0.88 | ADORA1 (0.44) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL8397308 | 0.85 | ADORA2A (0.42) | ALDH1A1GAAADORA3ADORA2BADORA2A | |
| SCHEMBL8397023 | 0.84 | ADORA2B (0.44) | GAAMAPTADORA3ADORA2BADORA2A | |
| SCHEMBL7436318 | 0.83 | ADORA1 (0.46) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL8705434 | 0.82 | ADORA1 (0.39) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL7279799 | 0.81 | CNR2 (0.40) | ALDH1A1KMT2AMEN1TDP1ADORA3 | |
| SCHEMBL7269080 | 0.80 | CNR2 (0.39) | ALDH1A1KMT2AMEN1MAPTADORA3 | |
| SCHEMBL14267083 | 0.80 | LMNA (0.41) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL7270332 | 0.78 | DHFR (0.48) | ALDH1A1KMT2AMEN1MAPTTSHR | |
| SCHEMBL8710355 | 0.78 | TDP1 (0.35) | ALDH1A1LMNAGAATDP1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070934-A1 | KW-3902 CONJUGATES THAT DO NOT CROSS THE BLOOD-BRAIN BARRIER | MUGERDITICHIAN MARK | 2008-03-20 | — | — | US | disclosed |
| US-20080070934-A1 | KW-3902 CONJUGATES THAT DO NOT CROSS THE BLOOD-BRAIN BARRIER | MUGERDITICHIAN MARK | 2008-03-20 | — | — | US | disclosed |
| WO-2008024277-A2 | KW-3902 CONJUGATES THAT DO NOT CROSS THE BLOOD-BRAIN BARRIER | NOVACARDIA, INC. (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070934-A1 | KW-3902 CONJUGATES THAT DO NOT CROSS THE BLOOD-BRAIN BARRIER | DCX, FLT4, KDR | ALDH1A1 893/4885KMT2A 765/4885MEN1 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.