Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.42 |
| ▸ | MAOA | P21397 | 10/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209631 | 0.90 | S1PR5 (0.51) | MAOBMAOAGSK3BBACE1KCNH2 | |
| SCHEMBL8209192 | 0.86 | MMP13 (0.49) | MAOBMAOAKCNH2NPC1RAB9A | |
| SCHEMBL8213085 | 0.82 | MMP13 (0.46) | KCNH2NPC1POLBRAB9APARP10 | |
| SCHEMBL8209566 | 0.78 | POLB (0.45) | MAOBMAOAPOLBRAB9APARP10 | |
| SCHEMBL8212956 | 0.78 | MMP13 (0.42) | MAOBPOLB | |
| SCHEMBL8209442 | 0.77 | KDM1A (0.43) | KCNH2NPC1RAB9APARP10SCN3A | |
| SCHEMBL8209387 | 0.75 | S1PR5 (0.42) | MAOBMAOANPC1RAB9AS1PR5 | |
| SCHEMBL8211587 | 0.74 | S1PR1 (0.42) | MAOBMAOAS1PR5 | |
| SCHEMBL8211593 | 0.74 | ALOX5 (0.52) | KCNH2PARP10SCN3A | |
| SCHEMBL8210831 | 0.74 | BTK (0.35) | MAOBMAOAKCNH2SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114361-A | INHIBITORS OF MATRIX METALLOPROTEINASES AND REPROLYSIN; ADMINISTERING TO TREAT CONDITIONS WHICH CAN BE TREATED BY THE INHIBITION OF THESE ENZYMES | PFIZER INC. (US) | 2000-09-05 | — | — | US | claimed |