Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.38 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209387 | 0.90 | S1PR5 (0.42) | FFAR1ALDH1A1LMNAMMP2MMP3 | |
| SCHEMBL8213085 | 0.90 | MMP13 (0.46) | KCNH2PARP10SCN4AMMP1MMP2 | |
| SCHEMBL8210831 | 0.89 | BTK (0.35) | KDM1AKCNH2SCN3ACYP19A1HTT | |
| SCHEMBL8209566 | 0.85 | POLB (0.45) | KDM1APARP10ALDH1A1SMN1; SMN2MMP1 | |
| SCHEMBL8209192 | 0.85 | MMP13 (0.49) | KDM1AKCNH2PARP10MMP13NPC1 | |
| SCHEMBL8208991 | 0.85 | NPC1 (0.41) | KDM1AFFAR1HPGDSMN1; SMN2FFAR2 | |
| SCHEMBL8201643 | 0.84 | ALOX5 (0.40) | KCNH2PARP10HTTFFAR1MMP13 | |
| SCHEMBL8211593 | 0.84 | ALOX5 (0.52) | KCNH2SCN3APARP10HTTMMP13 | |
| SCHEMBL8211587 | 0.82 | S1PR1 (0.42) | KDM1AFFAR1ALDH1A1 | |
| SCHEMBL8209631 | 0.77 | S1PR5 (0.51) | KDM1AKCNH2PARP10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114361-A | INHIBITORS OF MATRIX METALLOPROTEINASES AND REPROLYSIN; ADMINISTERING TO TREAT CONDITIONS WHICH CAN BE TREATED BY THE INHIBITION OF THESE ENZYMES | PFIZER INC. (US) | 2000-09-05 | — | — | US | claimed |