Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12216811 | 1.00 | PTGS2 (0.57) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23485348 | 1.00 | PTGS2 (0.57) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9532125 | 0.90 | KMT2A (0.56) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20418679 | 0.88 | L3MBTL1 (0.52) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10795444 | 0.86 | PTGS2 (0.51) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2000769 | 0.86 | L3MBTL1 (0.54) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10797135 | 0.85 | PTGS2 (0.50) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8930325 | 0.84 | LMNA (0.52) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8930328 | 0.84 | LMNA (0.52) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7740325 | 0.84 | SLC1A3 (0.50) | PTGS2KMT2ASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638513-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20060178366-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178366-A1 | Compounds for the treatment of inflammatory disorders | MMP12, ADAMTS1, TNF | PTGS2 410/4885KMT2A 3845/4885SLC1A3 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.