Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930325 | 1.00 | LMNA (0.52) | LMNAL3MBTL1ALDH1A1MMP8RCE1 | |
| SCHEMBL21843008 | 0.90 | ALDH1A1 (0.53) | LMNAL3MBTL1ALDH1A1MMP8RCE1 | |
| SCHEMBL21843005 | 0.90 | ALDH1A1 (0.53) | LMNAL3MBTL1ALDH1A1MMP8RCE1 | |
| SCHEMBL9116854 | 0.86 | L3MBTL1 (0.54) | LMNAL3MBTL1ALDH1A1MMP8RCE1 | |
| SCHEMBL23485348 | 0.84 | PTGS2 (0.57) | LMNAL3MBTL1ALDH1A1MMP8PIN1 | |
| SCHEMBL12216811 | 0.84 | PTGS2 (0.57) | LMNAL3MBTL1ALDH1A1MMP8PIN1 | |
| SCHEMBL8215545 | 0.84 | PTGS2 (0.57) | LMNAL3MBTL1ALDH1A1MMP8PIN1 | |
| SCHEMBL1362201 | 0.83 | SLC1A3 (0.51) | LMNAL3MBTL1ALDH1A1MMP8RCE1 | |
| SCHEMBL1362199 | 0.83 | SLC1A3 (0.51) | LMNAL3MBTL1ALDH1A1MMP8RCE1 | |
| SCHEMBL1487164 | 0.83 | SLC1A3 (0.51) | LMNAL3MBTL1ALDH1A1MMP8RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577040-B1 | Process for the preparation of (3R,5S)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxy-hexanoic acid, tert.-butyl ester | HOECHST AG (DE) | 1997-09-24 | — | — | EP | claimed |
| US-5399722-A | Process for preparing tert-butyl (3R,5S)-6-hydroxy-3,5--O--isopropylidene-3,5-dihydroxyhexanoate | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | claimed |
| JP-6087851-A | — | — | None | — | — | JP | disclosed |
| US-5399722-A | Process for preparing tert-butyl (3R,5S)-6-hydroxy-3,5--O--isopropylidene-3,5-dihydroxyhexanoate | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | disclosed |
| JP-H0687851-A | PREPARATION OF TERT-BUTYL (3R,5S)-6-HYDROXY-2,5-O-ISOPROPYLIDENE-3,5-DIHYDROXYHEXANOATE | HOECHST AG | 1994-03-29 | — | — | JP | disclosed |