Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 5/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909838 | 0.89 | CYP1A2 (0.62) | LTA4HALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17283659 | 0.87 | LTA4H (1.00) | LTA4HALDH1A1HTTMEN1KMT2A | |
| SCHEMBL491503 | 0.87 | LTA4H (1.00) | LTA4HALDH1A1HTTMEN1KMT2A | |
| Phosphine SCHEMBL28324113 | 0.84 | LTA4H (0.95) | LTA4HALDH1A1HTTMEN1KMT2A | |
| Diphenylether SCHEMBL818919 | 0.84 | LTA4H (0.94) | LTA4HALDH1A1HTTMEN1KMT2A | |
| SCHEMBL851498 | 0.84 | RAB9A (0.70) | ALDH1A1HTTMAPTSMN1; SMN2HPGD | |
| Diphenylether SCHEMBL28869227 | 0.84 | LTA4H (0.94) | LTA4HALDH1A1HTTMEN1KMT2A | |
| SCHEMBL1980006 | 0.84 | MTNR1B (0.66) | LTA4HALDH1A1PGRSMN1; SMN2 | |
| Diphenylether SCHEMBL27827099 | 0.82 | LTA4H (0.90) | LTA4HALDH1A1HTTMEN1KMT2A | |
| SCHEMBL21340447 | 0.81 | PGR (0.53) | LTA4HALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019720-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998027427-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |