Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203167 | 0.85 | CRHBP (0.50) | L3MBTL1CES2CES1ALDH1A1KMT2A | |
| SCHEMBL5615513 | 0.85 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL585143 | 0.84 | HCAR2 (0.51) | L3MBTL1CES2CES1ALDH1A1CYP3A4 | |
| SCHEMBL6242067 | 0.84 | HCAR2 (0.51) | L3MBTL1CES2CES1ALDH1A1CYP3A4 | |
| SCHEMBL5693685 | 0.84 | HCAR2 (0.51) | L3MBTL1CES2CES1ALDH1A1CYP3A4 | |
| SCHEMBL5615720 | 0.83 | L3MBTL1 (0.40) | L3MBTL1CES2CES1ALDH1A1CYP3A4 | |
| SCHEMBL3505279 | 0.82 | L3MBTL1 (0.43) | L3MBTL1CES2CES1KMT2AKDM4E | |
| Methane SCHEMBL28580094 | 0.82 | HCAR2 (0.50) | L3MBTL1CES2CES1ALDH1A1CYP3A4 | |
| SCHEMBL24991815 | 0.81 | L3MBTL1 (0.42) | L3MBTL1CES2CES1ALDH1A1KMT2A | |
| SCHEMBL9637379 | 0.80 | L3MBTL1 (0.44) | L3MBTL1CES2CES1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3020704-A2 | CRYSTALLINE POLYMORPHS OF CLEVIDIPINE BUTYRATE | Laboratorios Lesvi, S.L. (ES) | 2016-05-18 | — | — | EP | disclosed |
| EP-2386544-B1 | Preparation of dihydropyridines | LESVI LABORATORIOS SL (ES) | 2016-02-10 | — | — | EP | disclosed |
| US-8455655-B2 | Preparation of dihydropyridines | LABORATORIOS LESVI, S.L. (ES) | 2013-06-04 | — | — | US | disclosed |
| US-8268772-B2 | Depot preparations | SYMRISE AG (DE) | 2012-09-18 | — | — | US | disclosed |
| EP-2386544-A1 | Preparation of dihydropyridines | Laboratorios Lesvi, S.L. (ES) | 2011-11-16 | — | — | EP | disclosed |
| US-20110275825-A1 | PREPARATION OF DIHYDROPYRIDINES | LABORATORIOS LESVI, S.A. (ES) | 2011-11-10 | — | — | US | disclosed |
| US-20110253123-A1 | FLOW DIRECTING DEVICE FOR A COOKING APPLIANCE | RATIONAL AG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20060111269-A1 | Depot preparations | SYMRISE AG (DE) | 2006-05-25 | — | — | US | disclosed |
| US-20030114352-A1 | Depot preparations | SYMRISE GMBH & CO. KG (DE) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275825-A1 | PREPARATION OF DIHYDROPYRIDINES | CACNA1C, CACNA1D, CACNB4 | L3MBTL1 4339/4885CES2 916/4885CES1 796/4885 |
| US-20030114352-A1 | Depot preparations | FABP4, LIPE, GPR119 | L3MBTL1 4773/4885CES2 9/4885CES1 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.