Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAFG | O15525 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534725 | 0.87 | CASP3 (0.55) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL5406043 | 0.86 | TDP1 (0.56) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL8525642 | 0.82 | TDP1 (0.67) | FOLH1TDP1CAPN1MEN1ABL1 | |
| SCHEMBL2037323 | 0.82 | TDP1 (0.51) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL20827735 | 0.79 | FOLH1 (0.51) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL7577396 | 0.78 | TDP1 (0.64) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL5804890 | 0.77 | TDP1 (0.59) | FOLH1TDP1CAPN1MEN1ABL1 | |
| SCHEMBL29946177 | 0.76 | TDP1 (0.53) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL29802482 | 0.76 | TDP1 (0.53) | CASP3CASP1CASP2CASP7CASP8 | |
| SCHEMBL25417015 | 0.76 | TDP1 (0.77) | FOLH1TDP1CAPN1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511039-B2 | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | MYRIAD GENETICS, INCORPORATED (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276408-A1 | Beta-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins | SERPINB1, SERPINE1, SERPINA2 | CASP3 959/4885CASP1 197/4885CASP2 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.