Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153203 | 0.64 | HTR2A (0.44) | HTR2A | |
| SCHEMBL14733730 | 0.58 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL4553237 | 0.51 | SLC2A1 (0.41) | HTR2A | |
| SCHEMBL29481018 | 0.49 | S100A4 (0.58) | — | |
| SCHEMBL5712107 | 0.49 | S100A4 (0.58) | — | |
| SCHEMBL3385148 | 0.49 | MAOA (0.38) | — | |
| SCHEMBL19976713 | 0.47 | KEAP1 (0.36) | HTR2A | |
| SCHEMBL933891 | 0.47 | S100A4 (0.63) | — | |
| SCHEMBL3141116 | 0.47 | S100A4 (0.63) | — | |
| SCHEMBL28069500 | 0.47 | S100A4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146695-A1 | ACYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |