Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822377 | 0.86 | CDK1 (0.65) | NUDT1APPMAPK1EGFRKDR | |
| SCHEMBL9609211 | 0.82 | MAPK1 (0.64) | NUDT1APPMAPK1HTTTAAR1 | |
| SCHEMBL5695061 | 0.81 | CTSL (0.53) | NUDT1MAPK1HTTTAAR1IP6K1 | |
| SCHEMBL17933838 | 0.80 | NUDT1 (1.00) | NUDT1APPMAPK1HTTTAAR1 | |
| SCHEMBL10838740 | 0.80 | NUDT1 (0.41) | NUDT1APPCDK1TLR8TLR7 | |
| SCHEMBL6950876 | 0.79 | MPO (0.56) | NUDT1APPCDK1HSD17B10CYP2D6 | |
| SCHEMBL8826353 | 0.79 | CHUK (0.50) | NUDT1MAPK1EGFRCDK1TLR8 | |
| SCHEMBL8826182 | 0.79 | APP (0.47) | NUDT1APPHTTTLR8TLR7 | |
| SCHEMBL9792866 | 0.78 | APP (0.57) | NUDT1APPMAPK1HTTTAAR1 | |
| SCHEMBL6948069 | 0.77 | MPO (0.47) | NUDT1CDK1TLR8TLR7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279007-A1 | Compounds for Improving mRNA Splicing | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2023-09-07 | — | — | US | disclosed |
| US-20230279007-A1 | Compounds for Improving mRNA Splicing | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2023-09-07 | — | — | US | disclosed |
| US-11702417-B2 | Compounds for improving mRNA splicing | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-18 | — | — | US | disclosed |
| US-11702417-B2 | Compounds for improving mRNA splicing | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-18 | — | — | US | disclosed |
| EP-4115882-A1 | COMPOUNDS FOR IMPROVING MRNA SPLICING | The General Hospital Corporation (US) | 2023-01-11 | — | — | EP | disclosed |
| US-20200283441-A1 | Compounds for Improving mRNA Splicing | THE GENERAL HOSPITAL CORPORATION | 2020-09-10 | — | — | US | disclosed |
| US-10676475-B2 | Compounds for improving mRNA splicing | THE GENERAL HOSPITAL CORPORATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20180118748-A1 | Compounds for Improving mRNA Splicing | THE GENERAL HOSPITAL CORPORATION | 2018-05-03 | — | — | US | disclosed |
| WO-2016115434-A1 | COMPOUNDS FOR IMPROVING MRNA SPLICING | THE GENERAL HOSPITAL CORPORATION (US) | 2016-07-21 | — | — | WO | disclosed |
| US-9151883-B2 | Cellulose acylate film, retardation film, polarizer and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2015-10-06 | — | — | US | disclosed |
| US-8158220-B2 | Cellulose acylate film, retardation film, polarizer and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158220-B2 | Cellulose acylate film, retardation film, polarizer and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20120018685-A1 | Optical film, retardation film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |
| US-20120018685-A1 | Optical film, retardation film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-01-26 | — | — | US | disclosed |
| US-20110262661-A1 | Optical performance humidity dependency improving agent for cellulose acylate film | FUJIFILM CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20110262661-A1 | Optical performance humidity dependency improving agent for cellulose acylate film | FUJIFILM CORPORATION (JP) | 2011-10-27 | — | — | US | disclosed |
| US-20110255037-A1 | Cellulose acylate film, its production method, polarizer and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110255037-A1 | Cellulose acylate film, its production method, polarizer and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-10-20 | — | — | US | disclosed |
| US-20110076423-A1 | CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20110076423-A1 | CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279007-A1 | Compounds for Improving mRNA Splicing | RTCB, RBM17, HNRNPA2B1 | NUDT1 998/4885APP 604/4885MAPK1 4547/4885 |
| US-10676475-B2 | Compounds for improving mRNA splicing | RTCB, RBM17, HNRNPA2B1 | NUDT1 998/4885APP 604/4885MAPK1 4547/4885 |
| US-20180118748-A1 | Compounds for Improving mRNA Splicing | RTCB, RBM17, HNRNPA2B1 | NUDT1 998/4885APP 604/4885MAPK1 4547/4885 |
| US-11702417-B2 | Compounds for improving mRNA splicing | RTCB, RBM17, HNRNPA2B1 | NUDT1 998/4885APP 604/4885MAPK1 4547/4885 |
| US-20200283441-A1 | Compounds for Improving mRNA Splicing | RTCB, RBM17, HNRNPA2B1 | NUDT1 998/4885APP 604/4885MAPK1 4547/4885 |
| US-20110262661-A1 | Optical performance humidity dependency improving agent for cellulose acylate film | ALKBH1, ACOT7, ALKBH2 | NUDT1 476/4885APP 2292/4885MAPK1 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.