Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377842 | 0.82 | GRM5 (0.57) | GRM5KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL1390029 | 0.70 | VCP (0.63) | GRM5KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL364451 | 0.70 | VCP (0.58) | ALDH1A1MEN1NPC1CYP1A2CYP3A4 | |
| SCHEMBL8224583 | 0.70 | KDM4E (0.41) | EGLN1KDM4EALDH1A1NPC1CYP3A4 | |
| SCHEMBL19529556 | 0.68 | GRM5 (0.42) | GRM5KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL17053169 | 0.68 | ALDH1A1 (0.37) | FFAR1KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6429786 | 0.68 | GRM5 (0.62) | GRM5KDM4EALDH1A1MEN1NPC1 | |
| Neocuproine SCHEMBL10556003 | 0.67 | CCR1 (0.56) | EGLN1KDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL3720496 | 0.67 | CYP2A6 (0.43) | FFAR1GRM5KDM4EALDH1A1MEN1 | |
| SCHEMBL8544878 | 0.67 | LTB4R (0.45) | KDM4EALDH1A1MEN1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305049-A1 | Mri Contrast Agents for Diagnosis and Prognosis of Tumors | YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) | 2008-12-11 | — | — | US | disclosed |
| EP-1848466-A2 | MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006080022-A2 | MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305049-A1 | Mri Contrast Agents for Diagnosis and Prognosis of Tumors | TFRC, FOLR1, CD14 | FFAR1 799/4885FFAR4 1271/4885EGLN1 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.