Isosorbide

Isosorbide

SCHEMBL822850

OC1CO[C@@H]2C(O)CO[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 1/20 1.00
▸ LMNA P02545 1/20 1.00
▸ MAPT P10636 1/20 0.48
▸ BCHE P06276 1/20 0.33
▸ FUCA1 P04066 1/20 0.30
▸ GBA1 P04062 1/20 0.30
▸ GLA P06280 1/20 0.30
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isosorbide SCHEMBL9915547 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL83297 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL824823 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL12504733 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL5884995 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL24465084 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL9915550 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL2599531 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL15495 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL196416 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218157-A1 SCRATCH - RESISTANT POLYCARBONATE COMPOSITION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-07-04 — — US disclosed
WO-2023228804-A1 RESIN COMPOSITION, FILM, CARD, AND PASSPORT 三菱ケミカル株式会社 2023-11-30 — — WO disclosed
US-20230340259-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND MACROMONOMER COPOLYMER MITSUBISHI CHEMICAL CORPORATION (JP) 2023-10-26 — — US disclosed
EP-2573137-B1 SHEET FOR CARDS AND CARD MITSUBISHI CHEM CORP (JP) 2023-08-30 — — EP disclosed
WO-2023139134-A1 FUNCTIONALIZED POLY(ARYL ETHER SULFONES) COPOLYMERS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-07-27 — — WO disclosed
US-20230176495-A1 PIGMENT DISPERSION AND TONER CANON KABUSHIKI KAISHA (JP) 2023-06-08 — — US disclosed
WO-2022043376-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2022-03-03 — — WO disclosed
EP-2818499-B1 RESIN COMPOSITION AND MOLDED BODY OF SAME MITSUBISHI CHEM CORP (JP) 2022-01-12 — — EP disclosed
US-10815244-B2 Isoidide derivatives and methods of making and using same RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-10-27 — — US disclosed
WO-2020196146-A1 POLARIZING PLATE WITH RETARDATION LAYER 日東電工株式会社 2020-10-01 — — WO disclosed
US-20090105393-A1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-04-23 — — US disclosed
US-20090105393-A1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-04-23 — — US disclosed
US-20090105438-A1 POLYCARBONATE RESINS METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-23 — — US disclosed
US-20090105438-A1 POLYCARBONATE RESINS METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-23 — — US disclosed
US-20090105443-A1 ALIPHATIC POLYCARBONATES, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-04-23 — — US disclosed
US-20090105444-A1 ALIPHATIC DIOL-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-23 — — US disclosed
WO-2009033934-A1 POLYCARBONATE AND PROCESS FOR PRODUCING THE SAME STICHTING DUTCH POLYMER INSTITUTE (NL) 2009-03-19 — — WO disclosed
EP-2036937-A1 Polycarbonate and process for producing the same Stichting Dutch Polymer Institute (NL) 2009-03-18 — — EP disclosed
US-7365148-B2 Polycarbonate and process for producing the same TEIJIN LIMITED (JP) 2008-04-29 — — US disclosed
US-7365148-B2 Polycarbonate and process for producing the same TEIJIN LIMITED (JP) 2008-04-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815244-B2 Isoidide derivatives and methods of making and using same MIF, ITGB7, ITGB4 THRB 494/4885LMNA 4401/4885MAPT 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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