Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isosorbide SCHEMBL822850 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL83297 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL824823 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL12504733 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL5884995 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL24465084 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL9915550 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL2599531 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL15495 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL196416 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006830-A1 | POLYARYLETHER COPOLYMERS BASED ON DIOLS SUGAR ALCOHOLS | BASF SE (DE) | 2023-02-02 | — | — | WO | disclosed |
| WO-2022129139-A1 | POLYESTER POLYOLS COMPRISING ISOSORBIDE, ISOIDIDE OR ISOMANNIDE-DERIVED UNITS | BASF SE (DE) | 2022-06-23 | — | — | WO | disclosed |
| WO-2020053079-A1 | POLYARYLENE ETHER | BASF SE (DE) | 2020-03-19 | — | — | WO | disclosed |
| EP-2817314-B1 | METHOD OF MAKING ISOIDIDE | STICHTING WAGENINGEN RES (NL) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978769-B1 | NOVEL PROCESS FOR PREPARING POLYOL GLYCOSIDES | SOCIÉTÉ D'EXPLOITATION DE PRODUITS POUR LES IND CHIMIQUES SEPPIC (FR) | 2017-03-29 | — | — | EP | disclosed |
| EP-3056496-A1 | METHOD OF MAKING ISOIDIDE | Stichting Dienst Landbouwkundig Onderzoek (NL) | 2016-08-17 | — | — | EP | disclosed |
| US-9340552-B2 | Method of making isoidide | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-05-17 | — | — | US | disclosed |
| US-9340552-B2 | Method of making isoidide | ARCHER DANIELS MIDLAND COMPANY (US) | 2016-05-17 | — | — | US | disclosed |
| US-20140371472-A1 | METHOD OF MAKING ISOIDIDE | STICHTING DIENST LANDBOUWKUNDI (NL) | 2014-12-18 | — | — | US | disclosed |
| US-20140371472-A1 | METHOD OF MAKING ISOIDIDE | STICHTING DIENST LANDBOUWKUNDI (NL) | 2014-12-18 | — | — | US | disclosed |
| WO-2013125950-A1 | METHOD OF MAKING ISOIDIDE | STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) | 2013-08-29 | — | — | WO | disclosed |
| EP-1803773-B1 | POLYMERIZABLE LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL FILM MADE FROM THE COMPOSITION | NIPPON OIL CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-20120249928-A1 | LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2012-10-04 | — | — | US | disclosed |
| US-8199291-B2 | Liquid crystal display device having polymer-stabilized blue phase liquid crystal layer and transparent films | FUJIFILM CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| US-20120092426-A1 | CURABLE PHASE CHANGE INKS CONTAINING FUNCTIONALIZED ISOSORBIDES | XEROX CORPORATION (US) | 2012-04-19 | — | — | US | disclosed |
| US-20090322997-A1 | LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371472-A1 | METHOD OF MAKING ISOIDIDE | SI, HSD11B2, HSD11B1 | THRB 4597/4885LMNA 4552/4885MAPT 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.