Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isosorbide SCHEMBL822850 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL9915547 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL83297 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL12504733 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL5884995 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL24465084 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL9915550 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL2599531 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL15495 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 | |
| Isosorbide SCHEMBL196416 | 1.00 | THRB (1.00) | THRBLMNAMAPTBCHEFUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093781-B1 | METHOD FOR PRODUCING REMOVABLE PRESSURE-SENSITIVE ADHESIVES (PSAS) USING BIO-BASED STARTING MATERIALS | THE UNIV OF THE BASQUE COUNTRY (ES) | 2023-12-13 | — | — | EP | disclosed |
| US-20210002291-A1 | ISOIDIDE DERIVATIVES AND METHODS OF MAKING AND USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2021-01-07 | — | — | US | disclosed |
| US-10815244-B2 | Isoidide derivatives and methods of making and using same | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-10-27 | — | — | US | disclosed |
| WO-2019118571-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| US-20170066778-A1 | SOLUBILITY FOR TARGET COMPOUNDS | Aunova Medchem LLC (US) | 2017-03-09 | — | — | US | disclosed |
| WO-2017040459-A1 | IMPROVED SOLUBILITY FOR TARGET COMPOUNDS | Aunova Medchem LLC (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20160264726-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-09-15 | — | — | US | disclosed |
| US-8142682-B2 | Cholesteric multi-layers | SICPA HOLDING SA (CH) | 2012-03-27 | — | — | US | disclosed |
| US-8142682-B2 | Cholesteric multi-layers | SICPA HOLDING SA (CH) | 2012-03-27 | — | — | US | disclosed |
| US-20100178508-A1 | Cholesteric Multi-Layers | SICPA HOLDING S.A. (CH) | 2010-07-15 | — | — | US | disclosed |
| US-20100178508-A1 | Cholesteric Multi-Layers | SICPA HOLDING S.A. (CH) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815244-B2 | Isoidide derivatives and methods of making and using same | MIF, ITGB7, ITGB4 | THRB 494/4885LMNA 4401/4885MAPT 4330/4885 |
| US-20210002291-A1 | ISOIDIDE DERIVATIVES AND METHODS OF MAKING AND USING SAME | MIF, ITGB7, ITGB4 | THRB 494/4885LMNA 4401/4885MAPT 4330/4885 |
| US-20170066778-A1 | SOLUBILITY FOR TARGET COMPOUNDS | MIF, ITGB7, ITGB4 | THRB 252/4885LMNA 3708/4885MAPT 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.