Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592801 | 0.91 | AKT1 (0.33) | CCR5 | |
| SCHEMBL4584318 | 0.82 | PIK3C3 (0.31) | — | |
| SCHEMBL4581928 | 0.81 | CYP2C19 (0.38) | — | |
| SCHEMBL8242925 | 0.71 | PIK3C3 (0.42) | — | |
| SCHEMBL12346679 | 0.70 | L3MBTL1 (0.40) | — | |
| SCHEMBL8233993 | 0.70 | AKT1 (0.45) | — | |
| SCHEMBL4633196 | 0.68 | CYP2C19 (0.46) | — | |
| SCHEMBL8244308 | 0.67 | SCN9A (0.42) | — | |
| SCHEMBL16380561 | 0.66 | L3MBTL1 (0.40) | — | |
| SCHEMBL4583522 | 0.66 | AKT1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076423-A2 | INHIBITORS OF Akt ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |