Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242555 | 0.82 | CCR5 (0.31) | — | |
| SCHEMBL4581928 | 0.75 | CYP2C19 (0.38) | PIK3C3CYP2C19 | |
| SCHEMBL4592801 | 0.72 | AKT1 (0.33) | PIK3C3CYP2C19 | |
| SCHEMBL4633196 | 0.67 | CYP2C19 (0.46) | PIK3C3CYP2C19 | |
| SCHEMBL4583522 | 0.65 | AKT1 (0.41) | PIK3C3CYP2C19 | |
| SCHEMBL8243099 | 0.65 | AKT1 (0.47) | — | |
| SCHEMBL4592678 | 0.65 | AKT1 (0.46) | PIK3C3CYP2C19 | |
| SCHEMBL8242925 | 0.65 | PIK3C3 (0.42) | PIK3C3CYP2C19 | |
| SCHEMBL12346679 | 0.64 | L3MBTL1 (0.40) | PIK3C3CYP2C19 | |
| SCHEMBL4592495 | 0.64 | AKT1 (0.46) | PIK3C3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968568-A2 | INHIBITORS OF Akt ACTIVITY | SmithKline Beecham Corporation (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007076423-A2 | INHIBITORS OF Akt ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |