Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8245029 | 0.88 | HRH3 (0.48) | ALDH1A1CCR3HRH3MEN1KMT2A | |
| SCHEMBL8245727 | 0.86 | USP2 (0.56) | USP2ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL9046587 | 0.77 | CCR3 (0.49) | CCR3 | |
| SCHEMBL8245902 | 0.77 | ALDH1A1 (0.51) | USP2ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL19623526 | 0.74 | MAPT (0.52) | ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4773706 | 0.73 | CCR3 (0.59) | CCR3OPRM1 | |
| SCHEMBL6985304 | 0.73 | SIGMAR1 (0.46) | — | |
| SCHEMBL3576656 | 0.73 | LMNA (0.51) | USP2ALDH1A1HPGDKMT2ARAB9A | |
| SCHEMBL8243016 | 0.73 | LMNA (0.58) | ALDH1A1MEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL5842852 | 0.73 | SIGMAR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |