Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8245902 | 0.90 | ALDH1A1 (0.51) | USP2ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL19623526 | 0.87 | MAPT (0.52) | ALDH1A1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL8243176 | 0.86 | USP2 (0.44) | USP2ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3576656 | 0.85 | LMNA (0.51) | USP2ALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL11096321 | 0.85 | SIGMAR1 (0.56) | ALDH1A1RAB9AMAPTKMT2AMC4R | |
| Hydrochloric Acid SCHEMBL4809788 | 0.84 | LMNA (0.50) | ALDH1A1TSHRRAB9AMAPTLMNA | |
| SCHEMBL8243016 | 0.82 | LMNA (0.58) | ALDH1A1RAB9ATP53LMNANPSR1 | |
| SCHEMBL14262613 | 0.81 | KMT2A (0.43) | USP2ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL2378167 | 0.79 | KMT2A (0.70) | ALDH1A1HPGDSMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL11678483 | 0.78 | DRD2 (0.58) | ALDH1A1SMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |