Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243176 | 0.88 | USP2 (0.44) | HRH3MEN1ALDH1A1KMT2ACCR3 | |
| SCHEMBL6985304 | 0.80 | SIGMAR1 (0.46) | SCN5AHTR3A | |
| Hydrochloric Acid SCHEMBL5842852 | 0.79 | SIGMAR1 (0.45) | HTR3A | |
| SCHEMBL9046587 | 0.78 | CCR3 (0.49) | CCR3 | |
| SCHEMBL18502033 | 0.78 | L3MBTL1 (0.68) | HRH3L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL18501758 | 0.78 | L3MBTL1 (0.54) | L3MBTL1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL11793425 | 0.76 | SIGMAR1 (0.53) | KDM4E | |
| SCHEMBL11790502 | 0.75 | HTR1A (0.69) | HRH3L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL18502043 | 0.75 | L3MBTL1 (0.64) | HRH3L3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8245727 | 0.75 | USP2 (0.56) | SCN5AMEN1ALDH1A1KMT2ACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |