Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247376 | 0.88 | TP53 (0.36) | MEN1PABPC1KMT2ALMNATDP1 | |
| SCHEMBL8253078 | 0.77 | KDM4E (0.30) | — | |
| SCHEMBL8253057 | 0.75 | MEN1 (0.42) | MEN1PABPC1KMT2ALMNA | |
| SCHEMBL8247720 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL8253259 | 0.72 | KDM4E (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL8256657 | 0.70 | HPGD (0.44) | MEN1KMT2ALMNATDP1 | |
| SCHEMBL8258271 | 0.69 | LMNA (0.34) | LMNATDP1 | |
| SCHEMBL8246479 | 0.68 | MEN1 (0.43) | MEN1PABPC1KMT2ALMNATDP1 | |
| SCHEMBL8186296 | 0.68 | CSNK2A1 (0.34) | KMT2A | |
| SCHEMBL8255658 | 0.68 | MEN1 (0.42) | MEN1PABPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |