Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 11/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028674 | 0.89 | DPP4 (0.51) | TRHRRENDPP4CTSDLNPEP | |
| SCHEMBL4959538 | 0.88 | TRHR (0.64) | TRHRRENDPP4CTSDLNPEP | |
| SCHEMBL8258003 | 0.84 | TRHR (0.54) | TRHRRENDPP4CTSDLNPEP | |
| SCHEMBL8252513 | 0.80 | TRHR (0.78) | TRHRDPP4 | |
| SCHEMBL30595016 | 0.77 | CYP3A4 (0.57) | RENLNPEPACE2 | |
| SCHEMBL21828702 | 0.77 | CYP3A4 (0.57) | RENLNPEPACE2 | |
| SCHEMBL19345095 | 0.76 | TRHR (0.61) | TRHRRENCTSDLNPEP | |
| SCHEMBL4264574 | 0.76 | LNPEP (0.58) | TRHRRENCTSDLNPEPANPEP | |
| SCHEMBL29349749 | 0.74 | CYP3A4 (0.53) | RENLNPEPACE2 | |
| SCHEMBL29636378 | 0.74 | LNPEP (0.54) | RENCTSDLNPEPANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006096829-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | ROGER WILLIAMS HOSPITAL (US) | 2006-09-14 | — | — | WO | disclosed |