Sugi Predict

Sugi Predict / Compounds / SCHEMBL826656

SCHEMBL826656

SCHEMBL826656

CC(=O)C(=O)NCCCCC(N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSR P00390 1/20 0.52
▸ NOS2 P35228 5/20 0.50
▸ NOS1 P29475 4/20 0.50
▸ NOS3 P29474 3/20 0.50
▸ OTC P00480 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ TSHR P16473 1/20 0.50
▸ BLM P54132 1/20 0.49
▸ DPP7 Q9UHL4 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ ARG2 P78540 4/20 0.47
▸ ARG1 P05089 3/20 0.47
▸ GNAI3 P08754 1/20 0.45
▸ GNAO1 P09471 1/20 0.45
▸ GNAI1 P63096 1/20 0.45
▸ NOD1 Q9Y239 1/20 0.44
▸ DDAH1 O94760 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15631779 1.00 GSR (0.52) GSRNOS2NOS1NOS3OTC
SCHEMBL12028665 0.94 OTC (0.56) GSRNOS2NOS1NOS3OTC
SCHEMBL12520125 0.89 NOS2 (0.46) GSRNOS2NOS1NOS3OTC
SCHEMBL919222 0.87 KDM4E (0.56) GSRNOS2NOS1NOS3OTC
SCHEMBL236178 0.87 KDM4E (0.56) GSRNOS2NOS1NOS3OTC
SCHEMBL180969 0.87 KDM4E (0.56) GSRNOS2NOS1NOS3OTC
SCHEMBL6579587 0.86 GSR (0.48) GSRNOS2NOS1NOS3OTC
SCHEMBL686695 0.86 GSR (0.48) GSRNOS2NOS1NOS3OTC
SCHEMBL10063628 0.86 GSR (0.48) GSRNOS2NOS1NOS3OTC
Hydrochloric Acid SCHEMBL15669798 0.85 KDM4E (0.54) GSRNOS2NOS1NOS3OTC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 — — US disclosed
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 — — US disclosed
EP-3488870-B1 ANTI-CD70 ANTIBODY DRUG CONJUGATES AMBRX INC (US) 2024-03-20 — — EP disclosed
US-20230348547-A1 MODIFIED BOVINE G-CSF POLYPEPTIDES AND THEIR USES AMBRX INC (US) 2023-11-02 — — US disclosed
US-11786578-B2 Modified relaxin polypeptides and their uses AMBRX, INC. (US) 2023-10-17 — — US disclosed
US-11786578-B2 Modified relaxin polypeptides and their uses AMBRX, INC. (US) 2023-10-17 — — US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 — — US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 — — US disclosed
US-20230295320-A1 Anti-CD70 Antibody Drug Conjugates AMBRX, INC. (US) 2023-09-21 — — US disclosed
US-20230295320-A1 Anti-CD70 Antibody Drug Conjugates AMBRX, INC. (US) 2023-09-21 — — US disclosed
US-20080113412-A1 Blood plasma protein conjugated to apolipoproteins for use in treatment of metabolic disorders AMBRX, INC. (US) 2008-05-15 — — US disclosed
US-20080113412-A1 Blood plasma protein conjugated to apolipoproteins for use in treatment of metabolic disorders AMBRX, INC. (US) 2008-05-15 — — US disclosed
US-20080107680-A1 Modified Human Growth Hormone AMBRX, INC. (US) 2008-05-08 — — US disclosed
US-20080107680-A1 Modified Human Growth Hormone AMBRX, INC. (US) 2008-05-08 — — US disclosed
US-20080102124-A1 Modified Human Growth Hormone AMBRX, INC. (US) 2008-05-01 — — US disclosed
US-20080102124-A1 Modified Human Growth Hormone AMBRX, INC. (US) 2008-05-01 — — US disclosed
US-20080102125-A1 Modified Human Growth Hormone AMBRX, INC. (US) 2008-05-01 — — US disclosed
US-20080102125-A1 Modified Human Growth Hormone AMBRX, INC. (US) 2008-05-01 — — US disclosed
US-7332571-B2 Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses AMBRX, INC. (US) 2008-02-19 — — US disclosed
US-7332571-B2 Non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, therapeutic, diagnostic, and other biotechnology uses AMBRX, INC. (US) 2008-02-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037405-B2 Anti-CD70 antibody drug conjugates CD74, CD63, CD47 GSR 4873/4885NOS2 1667/4885NOS1 2210/4885
US-20080102124-A1 Modified Human Growth Hormone GHRHR, GHITM, GHSR GSR 3937/4885NOS2 3159/4885NOS1 3620/4885
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF TLR3, TLR1, TLR9 GSR 4178/4885NOS2 4241/4885NOS1 4297/4885
US-20080102125-A1 Modified Human Growth Hormone GHRHR, GHITM, GHSR GSR 3937/4885NOS2 3159/4885NOS1 3620/4885
US-20230348547-A1 MODIFIED BOVINE G-CSF POLYPEPTIDES AND THEIR USES CSF3R, GMFG, HDGF GSR 2625/4885NOS2 2298/4885NOS1 3226/4885
US-20080113412-A1 Blood plasma protein conjugated to apolipoproteins for use in treatment of metabolic disorders APOB, FABP1, HDLBP GSR 1482/4885NOS2 3517/4885NOS1 3836/4885
US-20230295320-A1 Anti-CD70 Antibody Drug Conjugates CD63, CD74, CD99 GSR 4870/4885NOS2 2216/4885NOS1 2705/4885
US-11786578-B2 Modified relaxin polypeptides and their uses RXFP1, RXFP2, RXFP3 GSR 3276/4885NOS2 396/4885NOS1 624/4885
US-20080107680-A1 Modified Human Growth Hormone GHRHR, GHITM, GHSR GSR 3937/4885NOS2 3159/4885NOS1 3620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.