Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.55 |
| ▸ | TYK2 | P29597 | 1/20 | 0.55 |
| ▸ | PYGL | P06737 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272739 | 0.85 | P2RX1 (0.72) | — | |
| SCHEMBL14450814 | 0.84 | RAB9A (0.51) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL24211468 | 0.83 | TAS1R3 (0.57) | ALDH1A1RAB9ANPC1MAPTSIGMAR1 | |
| SCHEMBL11438420 | 0.81 | MEN1 (0.60) | MEN1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL2227567 | 0.79 | MEN1 (0.76) | MEN1KMT2ATP53RAB9ANPC1 | |
| SCHEMBL13026637 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPT | |
| SCHEMBL11573735 | 0.79 | MEN1 (0.65) | MEN1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL13689945 | 0.79 | MEN1 (0.72) | MEN1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL11432595 | 0.78 | MEN1 (0.61) | MEN1KMT2AALDH1A1TP53RAB9A | |
| SCHEMBL2009922 | 0.78 | MEN1 (0.65) | MEN1KMT2AALDH1A1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | MEN1 1433/4885KMT2A 4490/4885ALDH1A1 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.