Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8287814 | 0.80 | ALDH1A1 (0.32) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8287325 | 0.74 | GAA (0.42) | ALDH1A1MAPTGAAHPGDLMNA | |
| SCHEMBL5872167 | 0.71 | MAT2A (0.34) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8285115 | 0.70 | BPTF (0.36) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8287801 | 0.70 | ALDH1A2 (0.37) | ALDH1A1MAPTKMT2AKDM4EL3MBTL1 | |
| SCHEMBL24474402 | 0.69 | KRAS (0.39) | MAPTKDM4EMAPK11MAPK14NPSR1 | |
| SCHEMBL8285132 | 0.69 | APP (0.40) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL8287898 | 0.68 | LMNA (0.38) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8287816 | 0.68 | ALPL (0.40) | KDM4ETP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24459972 | 0.66 | KRAS (0.44) | P2RX7MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005091857-A2 | 1,6-NAPHTHYRIDINE AND 1,8-NAPHTHYRIDINE DERIVATIVES AND THEIR USE TO TREAT DIABETES AND RELATED DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
| WO-2003027112-A1 | 1, 8-NAPHTHYRIDINE DERIVATIVES AS ANTIDIABETICS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |