Soyasapogenol A

Soyasapogenol A

SCHEMBL828826

CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@](C)(CO)[C@@H]5CC[C@@]4(C)[C@]3(C)CC[C@@]2(C)[C@H](O)[C@@H]1O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.73
PTPN1 P18031 7/20 0.67
F3 P13726 3/20 0.67
USP2 O75604 2/20 0.67
LMNA P02545 1/20 0.67
CYP3A4 P08684 1/20 0.67
USP7 Q93009 1/20 0.67
SLCO1B3 Q9NPD5 1/20 0.67
SLCO1B1 Q9Y6L6 1/20 0.67
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
AKR1B10 O60218 1/20 0.59
AKR1B1 P15121 1/20 0.59
TOP2A P11388 1/20 0.58
EGFR P00533 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Soyasapogenol A SCHEMBL16431091 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
Soyasapogenol A SCHEMBL21886589 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
Soyasapogenol A SCHEMBL5887946 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
Soyasapogenol A SCHEMBL16431093 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
Soyasapogenol A SCHEMBL6241027 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
Soyasapogenol A SCHEMBL5887575 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
Soyasapogenol A SCHEMBL24626884 1.00 ALOX5 (0.73) ALOX5PTPN1F3USP2LMNA
SCHEMBL5887703 0.89 ALOX5 (0.67) ALOX5PTPN1F3USP2LMNA
SCHEMBL5887733 0.89 ALOX5 (0.67) ALOX5PTPN1F3USP2LMNA
Soyasapogenol B SCHEMBL12509509 0.89 ALOX5 (0.78) ALOX5PTPN1F3USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367305-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-12-04 US claimed
WO-2024177490-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME 서울대학교산학협력단 2024-08-29 WO claimed
US-12041907-B2 Cellulose-synthase-like enzymes and uses thereof YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-07-23 US claimed
CN-111993739-B Transparent polyester film for multilayer coextrusion optics and preparation method thereof 宁波长阳科技股份有限公司 2023-10-03 CN claimed
US-20220403437-A1 GLUCURONOSYLTRANSFERASE, GENE ENCODING SAME AND METHOD FOR USING THE SAME OSAKA UNIVERSITY (JP) 2022-12-22 US claimed
EP-4052701-A1 COMPOSITION FOR TGR5 ACTIVATION Suntory Holdings Limited (JP) 2022-09-07 EP claimed
EP-4046479-A1 GLUCURONYLTRANSFERASE, GENE ENCODING SAME AND METHOD FOR USING SAME OSAKA UNIVERSITY (JP) 2022-08-24 EP claimed
CN-114829577-A Glucuronic acid transferase, gene encoding the same, and method for using the same 国立大学法人大阪大学 2022-07-29 CN claimed
US-20220217934-A1 CELLULOSE-SYNTHASE-LIKE ENZYMES AND USES THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-07-14 US claimed
CN-114555105-A TGR5 activating composition 三得利控股株式会社 2022-05-27 CN claimed
WO-2004037180-A2 COMPOSITIONS THAT TREAT OR INHIBIT PATHOLOGICAL CONDITIONS ASSOCIATED WITH INFLAMMATORY RESPONSE METAPROTEOMICS, LLC (US) 2004-05-06 WO claimed
US-20040086580-A1 Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response META PROTEOMICS, LLC 2004-05-06 US claimed
EP-1411959-A1 CURCUMINOID COMPOSITIONS EXHIBITING SYNERGISTIC INHIBITION OF THE EXPRESSION AND/OR ACTIVITY OF CYCLOOXYGENASE-2 Metaproteomics, LLC (US) 2004-04-28 EP claimed
US-20030190403-A1 Soybean processed food NATIONAL AGRICULTURAL RESEARCH ORGANIZATION (JP) 2003-10-09 US claimed
US-20030108628-A1 Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2 FORTRESS CREDIT CORP. (AS COLLATERAL AGENT) 2003-06-12 US claimed
WO-2003007975-A1 CURCUMINOID COMPOSITIONS EXHIBITING SYNERGISTIC INHIBITION OF THE EXPRESSION AND/OR ACTIVITY OF CYCLOOXYGENASE-2 METAPROTEOMICS, LLC (US) 2003-01-30 WO claimed
US-20020077350-A1 Compositions exhibiting synergistic inhibition of the expression and/or activity of clyclooxygenase-2 ASHNI NATURACEUTICALS, INC. 2002-06-20 US claimed
US-20020068098-A1 Combinations of diterpene triepoxide lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2 ASHNI NATURACEUTICALS, INC. 2002-06-06 US claimed
WO-2002009698-A1 COMPOSITIONS EXHIBITING SYNERGISTIC INHIBITION OF THE EXPRESSION AND/OR ACTIVITY OF CYCLOOXYGENASE-2 ASHNI NATURACEUTICALS, INC. (US) 2002-02-07 WO claimed
US-5770223-A TOPICAL APPLICATION OF MIXTURES OF PLANT EXTRACTS CONTAINING SAPONINS(OR DERIVATIVES) LVMH RECHERCHE (FR) 1998-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040086580-A1 Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response HPGDS, TPSB2, TPSG1 ALOX5 296/4885PTPN1 791/4885F3 565/4885
US-20250367305-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME ALB, TNNC1, MYOF ALOX5 3541/4885PTPN1 1058/4885F3 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.