Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.34 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628934 | 0.97 | ALDH1A1 (0.45) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL828854 | 0.89 | TLR2 (0.41) | ALDH1A1LMNALPAR1LPAR3LPAR2 | |
| SCHEMBL10196084 | 0.88 | TLR2 (0.32) | ALDH1A1LMNALPAR1LPAR3 | |
| SCHEMBL15686246 | 0.84 | TLR2 (0.34) | LPAR1LPAR3LPAR2 | |
| SCHEMBL9978168 | 0.81 | MAPK1 (0.44) | ALDH1A1PRKCAMAPTSMN1; SMN2 | |
| SCHEMBL13627386 | 0.80 | DGKA (0.46) | ALDH1A1LMNAPRKCAMAPTTDP1 | |
| SCHEMBL27167190 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL14305765 | 0.79 | TLR2 (0.32) | LPAR1LPAR3 | |
| SCHEMBL14401811 | 0.79 | ENPP2 (0.41) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL14336806 | 0.79 | ALDH1A1 (0.30) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9731024-B2 | Nucleophilic catalysts for oxime linkage | BAXALTA INCORPORATED (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150024455-A1 | NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-01-22 | — | — | US | disclosed |
| US-8637640-B2 | Blood coagulation protein conjugates | BAXTER INTERNATIONAL INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8143347-B2 | Pegylation of recombinant blood coagulation factors in the presence of bound antibodies | BAXTER INTERNATIONAL INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-8071724-B2 | Factor VIII polymer conjugates | BAXTER INTERNATIONAL INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8053561-B2 | Pegylated factor VIII | BAXTER INTERNATIONAL INC. (US) | 2011-11-08 | — | — | US | disclosed |
| US-8003760-B2 | Factor VIII polymer conjugates | BAXTER INTERNATIONAL INC. (US) | 2011-08-23 | — | — | US | disclosed |
| US-7985839-B2 | Factor VIII polymer conjugates | BAXTER INTERNATIONAL INC. (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985838-B2 | Factor VIII polymer conjugates | BAXTER INTERNATIONAL INC. (US) | 2011-07-26 | — | — | US | disclosed |
| US-7982010-B2 | Factor VIII polymer conjugates | BAXTER INTERNATIONAL INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-20100173830-A1 | FACTOR VIII POLYMER CONJUGATES | BAXTER HEALTHCARE S.A. (CH) | 2010-07-08 | — | — | US | disclosed |
| US-20100173831-A1 | FACTOR VIII POLYMER CONJUGATES | BAXTER HEALTHCARE S.A. (CH) | 2010-07-08 | — | — | US | disclosed |
| US-20100168391-A1 | Pegylated Factor VIII | BAXTER INTERNATIONAL INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100113364-A1 | FACTOR VIII POLYMER CONJUGATES | BAXTER HEALTHCARE S.A. (CH) | 2010-05-06 | — | — | US | disclosed |
| US-20100113365-A1 | FACTOR VIII POLYMER CONJUGATES | BAXTER HEALTHCARE S.A. (CH) | 2010-05-06 | — | — | US | disclosed |
| US-20100093934-A1 | PEGYLATION OF RECOMBINANT BLOOD COAGULATION FACTORS IN THE PRESENCE OF BOUND ANTIBODIES | BAXTER INTERNATIONAL INC. (US) | 2010-04-15 | — | — | US | disclosed |
| US-7683158-B2 | Pegylated factor VIII | BAXTER INTERNATIONAL INC. (US) | 2010-03-23 | — | — | US | disclosed |
| US-7645860-B2 | Factor VIII polymer conjugates | BAXTER HEALTHCARE S.A. (CH) | 2010-01-12 | — | — | US | disclosed |
| US-20090076237-A1 | Factor VIII Polymer Conjugates | BAXTER HEALTHCARE S.A. (CH) | 2009-03-19 | — | — | US | disclosed |
| US-20070244301-A1 | Pegylated factor VIII | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093934-A1 | PEGYLATION OF RECOMBINANT BLOOD COAGULATION FACTORS IN THE PRESENCE OF BOUND ANTIBODIES | F8, F13B, F13A1 | ALDH1A1 2979/4885LMNA 815/4885PRKCA 2157/4885 |
| US-20100173830-A1 | FACTOR VIII POLYMER CONJUGATES | F8, F13B, F13A1 | ALDH1A1 3149/4885LMNA 1171/4885PRKCA 1603/4885 |
| US-20100173831-A1 | FACTOR VIII POLYMER CONJUGATES | F8, F13B, F13A1 | ALDH1A1 3149/4885LMNA 1171/4885PRKCA 1603/4885 |
| US-20090076237-A1 | Factor VIII Polymer Conjugates | F8, F13B, F13A1 | ALDH1A1 3149/4885LMNA 1171/4885PRKCA 1603/4885 |
| US-20100113365-A1 | FACTOR VIII POLYMER CONJUGATES | F8, F13B, F13A1 | ALDH1A1 3149/4885LMNA 1171/4885PRKCA 1603/4885 |
| US-20150024455-A1 | NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE | LPO, OGA, DAO | ALDH1A1 1457/4885LMNA 4302/4885PRKCA 2894/4885 |
| US-20070244301-A1 | Pegylated factor VIII | F8, F13B, F7 | ALDH1A1 3719/4885LMNA 623/4885PRKCA 2394/4885 |
| US-20100168391-A1 | Pegylated Factor VIII | F8, F13B, F7 | ALDH1A1 3719/4885LMNA 623/4885PRKCA 2394/4885 |
| US-20100113364-A1 | FACTOR VIII POLYMER CONJUGATES | F8, F13B, F13A1 | ALDH1A1 3149/4885LMNA 1171/4885PRKCA 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.