SCHEMBL829287

SCHEMBL829287

Cc1nc(-c2ccccc2)[nH]c1C(=S)S

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 5/20 0.46
MAPK1 P28482 2/20 0.46
CYP1A2 P05177 1/20 0.46
CASP1 P29466 1/20 0.46
CYP2C19 P33261 1/20 0.46
KDM4E B2RXH2 1/20 0.43
MAPT P10636 3/20 0.43
GAA P10253 3/20 0.42
NPY5R Q15761 1/20 0.42
HPGDS O60760 1/20 0.42
POLB P06746 3/20 0.41
HSD17B10 Q99714 2/20 0.41
USP2 O75604 1/20 0.41
TSHR P16473 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL829583 0.82 PIN1 (0.45) PIN1MAPK1CYP1A2CASP1CYP2C19
SCHEMBL11186386 0.78 GCGR (0.33) PIN1MAPK1KDM4EMAPTHSD17B10
SCHEMBL4607219 0.74 ERCC1 (0.56) PIN1MAPK1CYP1A2CASP1CYP2C19
SCHEMBL547135 0.73 PIN1 (0.56) PIN1MAPK1CYP1A2CASP1CYP2C19
SCHEMBL647088 0.72 PIN1 (0.59) PIN1MAPK1KDM4EMAPTGAA
SCHEMBL15442034 0.72 HSD17B10 (0.59) PIN1MAPK1CYP1A2CASP1CYP2C19
SCHEMBL11516210 0.71 MAPK13 (0.53) PIN1KDM4EMAPTGAAPOLB
SCHEMBL33678 0.70 KDM4E (0.50) PIN1MAPK1CYP1A2CASP1CYP2C19
SCHEMBL828058 0.70 ALDH1A1 (0.33) L3MBTL1ALDH1A1
SCHEMBL8306285 0.69 MAPT (0.51) PIN1CYP1A2KDM4EMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069443-B1 IMIDAZOLES, THEIR PRODUCTION AND THEIR USE IN PREVENTING CORROSION OF SILVER SHIKOKU CHEMICALS CORPORATION (JP) 1984-11-07 EP claimed
US-4394511-A Imidazole 4(5)-dithiocarboxylic acids or salts SHIKOKU CHEMICALS CORPORATION (JP) 1983-07-19 US claimed
EP-0069443-A1 Imidazoles, their production and their use in preventing corrosion of silver SHIKOKU CHEMICALS CORPORATION (JP) 1983-01-12 EP claimed
CN-108276567-A Ionic liquid is in the preparation of liquid crystal polyester as the purposes of catalyst and a kind of preparation method of liquid crystal polyester 金发科技股份有限公司 2018-07-13 CN disclosed
EP-1728898-B1 Electrolytes for the deposition of gold alloys ROHM & HAAS ELECT MAT (US) 2017-02-22 EP disclosed
US-8202448-B2 Liquid-crystalline polyester resin composition and connector using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-06-19 US disclosed
US-8142637-B2 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-27 US disclosed
US-20100163796-A1 LIQUID-CRYSTALLINE POLYESTER RESIN COMPOSITION AND CONNECTOR USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-01 US disclosed
US-7614145-B2 Method for manufacturing multilayer circuit board and resin base material ZEON CORPORATION (JP) 2009-11-10 US disclosed
CN-100496195-C Mulitilayer circuit board, resin base material, and its production method ZEON CORP (JP) 2009-06-03 CN disclosed
US-20090104463-A1 Gold alloy electrolytes ROHM AND HAAS ELECTRONIC MATERIALS LLC 2009-04-23 US disclosed
US-20030168634-A1 Liquid crystalline polyester resin composition for a connector SUMITOMO CHEMICAL COMPANY, LIMITED 2003-09-11 US disclosed
US-6512079-B2 Acylating aromatic diol and/or aromatic hydroxycarboxylic acid with fatty anhydride, then transesterifying, in presence of imidazole based compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-28 US disclosed
US-20020055607-A1 Liquid crystalline polyester and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-09 US disclosed
EP-1184401-A1 Liquid crystalline polyester and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-06 EP disclosed
EP-0069443-B1 IMIDAZOLES, THEIR PRODUCTION AND THEIR USE IN PREVENTING CORROSION OF SILVER SHIKOKU CHEMICALS CORPORATION (JP) 1984-11-07 EP disclosed
US-4469622-A Method for preventing rusting in silver by using novel imidazole-4(5)-dithiocarboxylic acids in organic solvent SHIKOKU CHEMICALS CORPORATION (JP) 1984-09-04 US disclosed
US-4431818-A Process of preparing imidazole 4(5) dithiocarboxylic acid SHIKOKU CHEMICAL CORPORATION (JP) 1984-02-14 US disclosed
US-4394511-A Imidazole 4(5)-dithiocarboxylic acids or salts SHIKOKU CHEMICALS CORPORATION (JP) 1983-07-19 US disclosed
EP-0069443-A1 Imidazoles, their production and their use in preventing corrosion of silver SHIKOKU CHEMICALS CORPORATION (JP) 1983-01-12 EP disclosed