Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294302 | 0.92 | DPP4 (0.49) | DPP7DPP4L3MBTL1EPHX2KMT2A | |
| SCHEMBL8294300 | 0.86 | KMT2A (0.48) | DPP7DPP4L3MBTL1KMT2AATM | |
| SCHEMBL7390477 | 0.81 | CYP2D6 (0.67) | CYP2D6KMT2ATAAR1ATMALDH1A1 | |
| SCHEMBL7497638 | 0.76 | CHRM2 (0.42) | DPP7DPP4CYP2D6EPHX2KMT2A | |
| SCHEMBL7497644 | 0.76 | CHRM2 (0.42) | DPP7DPP4CYP2D6EPHX2KMT2A | |
| SCHEMBL4278254 | 0.76 | L3MBTL1 (0.60) | L3MBTL1EPHX2KMT2AATMALDH1A1 | |
| SCHEMBL4283829 | 0.75 | CCR5 (0.62) | L3MBTL1EPHX2KMT2AATMALDH1A1 | |
| SCHEMBL7576695 | 0.74 | ATM (0.62) | L3MBTL1CYP2D6KMT2AATMALDH1A1 | |
| SCHEMBL11426703 | 0.74 | KCNH2 (0.53) | OPRM1SIGMAR1 | |
| SCHEMBL13434079 | 0.72 | CCR5 (0.63) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |