Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294306 | 0.92 | DPP7 (0.52) | DPP4L3MBTL1OPRM1SIGMAR1EPHX1 | |
| SCHEMBL8294300 | 0.83 | KMT2A (0.48) | DPP4L3MBTL1OPRM1OPRL1DPP7 | |
| SCHEMBL4278254 | 0.80 | L3MBTL1 (0.60) | L3MBTL1SIGMAR1EPHX1EPHX2KMT2A | |
| SCHEMBL158734 | 0.73 | SIGMAR1 (0.67) | L3MBTL1SIGMAR1 | |
| SCHEMBL4283829 | 0.73 | CCR5 (0.62) | L3MBTL1SIGMAR1EPHX2KMT2AATM | |
| SCHEMBL7576695 | 0.72 | ATM (0.62) | L3MBTL1EPHX1KMT2AATM | |
| SCHEMBL7390477 | 0.72 | CYP2D6 (0.67) | OPRM1SIGMAR1KMT2AATM | |
| SCHEMBL9543983 | 0.71 | SIGMAR1 (0.58) | L3MBTL1SIGMAR1KMT2A | |
| SCHEMBL8015490 | 0.71 | LTA4H (0.66) | SIGMAR1KMT2A | |
| SCHEMBL13434079 | 0.70 | CCR5 (0.63) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |