SCHEMBL19985038

SCHEMBL19985038

CCOC(=O)/C(=C/O)C1CCc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 4/20 0.46
ANO1 Q5XXA6 2/20 0.39
KCNQ2 O43526 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.38
FFAR1 O14842 2/20 0.38
MAPT P10636 1/20 0.38
NTRK1 P04629 2/20 0.37
ROCK1 Q13464 1/20 0.37
XBP1 P17861 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21538694 0.92 ALDH1A1 (0.43) MEN1KMT2AL3MBTL1ALDH1A1FFAR1
SCHEMBL21538768 0.91 ANO1 (0.41) PIN1ANO1MEN1KMT2AL3MBTL1
SCHEMBL8301042 0.91 PIN1 (0.47) PIN1ANO1KCNQ2MEN1KMT2A
SCHEMBL19985034 0.86 MEN1 (0.41) MEN1KMT2AL3MBTL1TDP1ALDH1A1
SCHEMBL21538767 0.85 PIN1 (0.52) PIN1ANO1KCNQ2MEN1KMT2A
SCHEMBL21538784 0.82 FFAR1 (0.41) MEN1KMT2AL3MBTL1ALDH1A1FFAR1
SCHEMBL19984882 0.82 PIN1 (0.46) PIN1ANO1KCNQ2
SCHEMBL7419740 0.81 PIN1 (0.51) PIN1ANO1KCNQ2L3MBTL1ALDH1A1
SCHEMBL4720088 0.80 PIN1 (0.52) PIN1MEN1KMT2AALDH1A1FFAR1
SCHEMBL21538766 0.80 NPSR1 (0.40) ALDH1A1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 PIN1 2117/4885ANO1 3784/4885KCNQ2 4502/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 PIN1 2117/4885ANO1 3784/4885KCNQ2 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.