SCHEMBL19985034

SCHEMBL19985034

CCOC(=O)/C(=C/O)C1Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
P2RX7 Q99572 1/20 0.40
MAPT P10636 5/20 0.39
ALDH1A1 P00352 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ATM Q13315 1/20 0.39
POLB P06746 2/20 0.38
TSHR P16473 1/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985038 0.86 PIN1 (0.46) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL21538694 0.84 ALDH1A1 (0.43) MEN1KMT2AALDH1A1L3MBTL1KDM4E
SCHEMBL21538768 0.83 ANO1 (0.41) MEN1KMT2AALDH1A1L3MBTL1KDM4E
SCHEMBL21538741 0.77 GLS (0.41) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL19984937 0.77 NFE2L2 (0.37) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL8301042 0.77 PIN1 (0.47) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL19985049 0.76 MEN1 (0.40) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL21538718 0.75 L3MBTL1 (0.38) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL21538784 0.74 FFAR1 (0.41) MEN1KMT2AMAPTALDH1A1L3MBTL1
SCHEMBL18918220 0.72 ATM (0.40) MEN1KMT2AMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3512843-B1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2021-10-20 EP disclosed
US-11136292-B2 Plant growth regulator compounds SYNGENTA PARTICIPATIONS AG (CH) 2021-10-05 US disclosed
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-10-31 US disclosed
WO-2018050477-A1 PLANT GROWTH REGULATOR COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11136292-B2 Plant growth regulator compounds FGF1, MST1, CDC20 MEN1 3340/4885KMT2A 4196/4885P2RX7 4816/4885
US-20190330148-A1 PLANT GROWTH REGULATOR COMPOUNDS FGF1, MST1, CDC20 MEN1 3340/4885KMT2A 4196/4885P2RX7 4816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.