Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | RIOK2 | Q9BVS4 | 5/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30884573 | 0.69 | RIOK2 (0.44) | RIOK2MKNK1MKNK2PTGES | |
| SCHEMBL9359135 | 0.67 | GRIK1 (0.50) | MAPT | |
| SCHEMBL8908156 | 0.66 | BCAT2 (0.43) | MAPT | |
| SCHEMBL31174412 | 0.65 | CYP2A6 (0.68) | MKNK1MKNK2 | |
| SCHEMBL3754419 | 0.65 | CYP2A6 (0.68) | MKNK1MKNK2 | |
| SCHEMBL8305252 | 0.64 | ATM (0.42) | PTGS1PTGS2GRIN1GRIN2BRIOK2 | |
| SCHEMBL30404451 | 0.64 | ATM (0.56) | — | |
| SCHEMBL9134640 | 0.63 | MAT2A (0.41) | PDE2ARIOK2MAT2AMAPTMKNK1 | |
| SCHEMBL25184403 | 0.63 | TSHR (0.47) | PTGS1PTGS2MAPTMKNK1MKNK2 | |
| SCHEMBL8993633 | 0.62 | MEN1 (0.39) | PSDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946544-A1 | HETEROCYCLYLURACIL | BAYER AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027082-A1 | HETEROCYCLYLURACIL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |