Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7188655 | 0.81 | SMN1; SMN2 (0.54) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20194121 | 0.80 | F2 (0.46) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL10401280 | 0.80 | F2 (0.46) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20194124 | 0.80 | F2 (0.46) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20194129 | 0.79 | F2 (0.45) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2481253 | 0.77 | F2 (0.59) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20194143 | 0.76 | ALDH1A1 (0.42) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20194134 | 0.76 | ALDH1A1 (0.45) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL20194123 | 0.76 | ALDH1A1 (0.47) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL231914 | 0.74 | PRSS1 (0.95) | F2PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005012304-A2 | TRIAZOLOPYRIMIDINE DERIVATIVES AS GLYCOGEN SYNTHASE KINASE 3 INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | WO | disclosed |