Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 8/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8366400 | 0.99 | GPR55 (0.39) | GPR55CNR1CNR2HTR4NOTUM | |
| SCHEMBL8305677 | 0.83 | HTR4 (0.43) | GPR55CNR1CNR2HTR4NOTUM | |
| SCHEMBL8304451 | 0.82 | NOTUM (0.38) | GPR55CNR1HTR4NOTUM | |
| Hydrochloric Acid SCHEMBL8366413 | 0.82 | HTR4 (0.43) | GPR55CNR1CNR2HTR4NOTUM | |
| Hydrochloric Acid SCHEMBL8366408 | 0.81 | NOTUM (0.37) | GPR55CNR1HTR4NOTUM | |
| SCHEMBL7810013 | 0.79 | NOTUM (0.36) | GPR55CNR1HTR4NOTUM | |
| Hydrochloric Acid SCHEMBL7946657 | 0.78 | NOTUM (0.36) | GPR55CNR1HTR4NOTUM | |
| SCHEMBL8305672 | 0.77 | DRD2 (0.44) | GPR55CNR1 | |
| Hydrochloric Acid SCHEMBL8369921 | 0.77 | DRD2 (0.45) | GPR55CNR1 | |
| SCHEMBL8304573 | 0.76 | HTR3A (0.35) | GPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863897-B1 | 5-PHENYL-3-(PIPERIDIN-4-YL)-1,3,4-OXADIAZOL-2(3H)-ONE DERIVATIVES FOR USE AS 5-HT4- OR H3-RECEPTOR LIGANDS | SYNTHELABO (FR) | 1999-06-16 | — | — | EP | disclosed |