Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310281 | 0.89 | CYP3A4 (0.50) | GAASMN1; SMN2POLBTSHR | |
| SCHEMBL7397775 | 0.78 | GAA (0.48) | CACNA1BGAAALOX15SMN1; SMN2TSHR | |
| SCHEMBL11213032 | 0.77 | CAPN1 (0.59) | CACNA1BGAAALOX15SMN1; SMN2TSHR | |
| SCHEMBL11209259 | 0.76 | CAPN1 (0.60) | GAAALOX15SMN1; SMN2TSHRCAPN9 | |
| SCHEMBL7363254 | 0.74 | CAPN9 (0.51) | POLBCAPN9 | |
| SCHEMBL1954172 | 0.73 | MMP1 (0.48) | CACNA1BTSHR | |
| SCHEMBL8308565 | 0.71 | CTSL (0.51) | GAASMN1; SMN2POLB | |
| SCHEMBL7357371 | 0.68 | CYP3A4 (0.49) | GAAALOX15SMN1; SMN2POLBTSHR | |
| SCHEMBL7352660 | 0.68 | MAPK1 (0.54) | TSHR | |
| SCHEMBL11195762 | 0.68 | FKBP1A (0.42) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |